For this last month of a tumultuous year, the theme is probably that of China’s ascendancy in the domain of the sciences as Chinese researchers churn out groundbreaking discoveries one after another. I don’t even have to include China’s moon mission for this as that has yet to yield any novel science.

• We might as well start with those first so here’s the story of it switching on its tokamak for real. This a fusion reactor that has plasma as hot as the temperature as the sun swirling around inside, held in place only the magnetic fields created by supercooled electromagnets. The promise of fusion power forever being just beyond the horizon is an old one and it’s still likelier than not that China’s effort to chase viable fusion energy will amount to nothing. But there’s no denying that they are in the race for real now.
• The other one is about China’s photon-based quantum computer it has named Jiuzang. Like Google’s Sycamore, this has been built to perform a single type of computation, the one here being known as boson sampling. This involves sending parallel streams of photons as inputs through a series of beam splitters to obtain a result. Apparently trying to simulate this calculation through conventional means takes so long as to be effectively, thus making this a second clear case of quantum supremacy. I have no idea however if this has any practical use.
• Still neither of these can match the significance of the next bit of science news: the announcement that Google’s DeepMind AI has effectively solved the protein folding problem. They proved this at an annual competition that involves predicting what shapes given strings of amino acids will fold into. While DeepMind’s solutions were not perfect, they are still so accurate as to essential invalidate every other approach. Despite the fact this means the careers of many scientists in the field have been upended, pretty much everyone is in agreement that this is a truly revolutionary advance that will change the entire biotech industry.
• Next is a paper about restoring sight by inducing the retinal ganglion cells in the eyes to regenerate. Techniques to restore youth to cells and turn back the epigenetic clock have long been the stuff of science-fiction so this is a case of it in reality. They achieved it engineering a virus to induce expression of transcription factors that can trigger mature cells that it infects to revert to an immature state. Tested in mice, this approach succeeded in repairing damage to the RGC axon and restoring sight. Naturally they are very interested to learn if this technique also works on neurons elsewhere in the brain and the spinal cord.
• Finally there is this bit of news about progress in developing so-called C4 rice. To cover some basics, different plants have different photosynthetic pathways and rice uses the less efficient C3 pathway. Maize on the other hand uses the more efficient C4 pathway. So C4 rice has been a sort of dream project for some time as the C4 pathway is theoretically up to 50% more efficient, so C4 rice would require less nitrogen and less water. This announcement is just about the early stage of assembling a functioning C4 biochemical pathway for rice and the real thing is still many years off but apparently this is still a pretty major advance.